Presentation for CDC advisers appears to cite nonexistent study to support claims about risk of vaccine preservative

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"CDC Presentation Cites Nonexistent Study on Thimerosal and Vaccine Safety"

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A presentation scheduled for a meeting of the US Centers for Disease Control and Prevention (CDC) vaccine advisers has come under scrutiny after it cited a non-existent study to support claims regarding the vaccine preservative thimerosal. The presentation, led by Lyn Redwood, a prominent figure in the anti-vaccine movement, alleged that a study conducted on newborn rats indicated long-term neuroimmune effects from thimerosal exposure. The reference cited was supposedly a 2008 study by Dr. Robert F. Berman, yet upon investigation, Berman confirmed that no such publication exists in the journal Neurotoxicology, and he expressed displeasure at the misrepresentation of his work. Instead, he had published a different study in a separate journal that reached contrary conclusions, finding no evidence linking thimerosal to adverse behaviors relevant to autism at vaccine exposure levels. This misattribution has raised concerns about the integrity of the evidence presented to the CDC's Advisory Committee on Immunization Practices.

The controversy surrounding Redwood’s presentation intensified due to the already contentious nature of thimerosal in vaccine discussions, particularly regarding claims that it may be linked to autism, a notion that has been widely discredited by scientific research. The presentation was hastily removed from the CDC website after the citation was flagged by Dr. David Boulware, an infectious diseases professor who questioned the validity of the claims made. The meeting agenda was altered to include this contentious topic after recent changes to the advisory panel, which saw the dismissal of previous members and the appointment of individuals with less experience in vaccine safety. This has sparked bipartisan concern among public health experts, including calls from Senator Bill Cassidy to postpone the meeting until the panel is adequately staffed with qualified experts. The issues surrounding the presentation and the broader implications for vaccine safety discussions highlight ongoing tensions within the public health community, particularly in relation to misinformation and the politicization of health policy under new leadership at the Health and Human Services department.

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Apresentationslated to be shared at this week’s meeting of vaccine advisers to the US Centers for Disease Control and Prevention claimed that a study in animals suggested that use of the vaccine preservative thimerosal can have “long-term consequences in the brain.”

But the study doesn’t appear to exist.

Lyn Redwood, a former leader of Children’s Health Defense, an anti-vaccine group that lists US Health and Human Services Secretary Robert F. Kennedy Jr. as a founder, is scheduled to give the presentation Thursday at a meeting of the CDC’s Advisory Committee on Immunization Practices.

The slides, posted online Tuesday, cite a 2008 study in the journal Neurotoxicology by “Berman RF, et al,” called “Low-level neonatal thimerosal exposure: Long-term consequences in the brain.” The presentation claimed that results from a study in newborn rats suggest long-term “neuroimmune effects” from the vaccine preservative.

The citation appears to refer toDr. Robert F. Berman, a professor emeritus at the University of California Davis, whose research has focused on brain injury and neurodevelopmental disorders.

However, “I don’t have a publication in Neurotoxicology by that title,” Berman told CNN. “The reference in the slide set, as far as I know – at least with me as a coauthor – does not exist.”

Berman did publish apaperwith a similar title in 2008, but it was in a different journal and involved different animals. It also came to dramatically different conclusions.

“My study was published in Toxicological Sciences and did not find evidence of thimerosal exposure at vaccine levels in mouse behaviors that we thought were relevant to autism,” Berman said. He was “concerned and displeased” that his research appeared to have been cited in this way in Redwood’s slides.

Redwood’s presentation wastaken offthe CDC website later Tuesday and replaced with a version that does not include Berman’s citation.

The citation was firstflaggedbyDr. David Boulware, an infectious diseases professor at the University of Minnesota, who told CNN, “The conclusion on that slide seemed really strong and definitive, and thus I wanted to look up the paper to see if the results matched their interpretation of it. … And I couldn’t find the citation.”

Neither Redwood nor HHS immediately responded to CNN’s request for comment on thepresentation.

The presentation already wascontroversialbecause thimerosal has been a focus of advocates who claim, against evidence, that it may cause autism because it contains a form of mercury. The preservative was taken out of most vaccines about 25 years ago as a precaution, and no evidence of neurodevelopmental effects has been found in multiple studies.

Redwood, though, said in avideoposted last month on Children’s Health Defense’s website that she believes thimerosal in pediatric vaccines led to her son’s autism.

The topic was a last-minute addition to the vaccine advisers’ agenda this week, sparking concerns among public health experts that it would raise debunked claims about vaccine safety. It was added after Kennedy dismissed all 17 previous experts on the influential vaccine panel, claiming they had conflicts of interest, and replaced them days later with eight newmembers.

Those members have raised concerns from the public health world and across the political spectrum, with Sen. Bill Cassidy, the Louisiana doctor who chairs the Senate Health, Education, Labor, and Pensions Committee,callingthis week for the meeting to be postponed “until the panel is fully staffed with more robust and balanced representation – as required by law – including those with more direct relevant expertise.”

It’s also not the first time a report in Kennedy’s realm has been found to have faulty citations. The initial version of the Trump administration’s Make America Healthy Again report, released last month and focused on children’s health, alsocitedsome studies that don’t exist. An HHS spokesperson called them “minor citation and formatting errors.”

In a hearing before the House Energy and Commerce Health Subcommittee on Tuesday, Kennedy was questioned by Rep. Raul Ruiz, a Democrat and doctor from California, about the MAHA report errors.

“Why did the report include a citation to sources that don’t even exist?” Ruiz asked. “How does that happen under your leadership?”

Kennedy insisted that “all of the foundational assertions in that report are accurate” and said the mistaken citations “were corrected within 24 hours.”

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Source: CNN